Hello.
I am Dr. Hyuk-chan Jo, Director of Cleor Clinic Uijeongbu Branch.
Have you ever considered Rejuran for skin regeneration, only to hesitate after reading reviews about the intense pain?
"I'm interested in Rejuran because it's effective for skin regeneration and fine lines, but I find it hard to decide because I've heard it's very painful.
I'm wondering if there's an option that reduces pain while maintaining the regenerative effects."
This is actually a question many people have.
Rejuran works by using salmon-derived PN (polynucleotide) to stimulate regeneration in the dermis.
While the results are clear, it is known to be quite stimulating during injection due to the high viscosity of the ingredient itself.
The upgraded option that addresses this pain burden is Uijeongbu Rejuran HB.
Today, I will summarize how Rejuran HB differs from the original Rejuran,
how it reduces pain while maintaining regenerative effects,
and how it can be combined with other Rejuran options.
What is Uijeongbu Rejuran HB?
👉 Uijeongbu Rejuran HB is an upgraded skin booster that adds hyaluronic acid (HA) and lidocaine (a local anesthetic) to the PN ingredient of the original Rejuran Healer.
It is a care option that approaches regeneration, hydration, and pain reduction all at once.
Rejuran is a PN-based skin booster developed by PharmaResearch in Korea.
While the original Rejuran Healer focuses on regenerative stimulation using only PN,
Rejuran HB (Hydro Booster) is a version that also contains hyaluronic acid and lidocaine,
and is often called "Painless Rejuran."
At our Uijeongbu branch, we offer Rejuran HB as a regular care option,
allowing you to access Rejuran's regenerative effects reliably while lowering the burden of pain.
Technical Features of Uijeongbu Rejuran HB
👉 Uijeongbu Rejuran HB is structured with three ingredients—PN, hyaluronic acid, and lidocaine—combined into a single formulation,
where each ingredient plays a different role to create synergy.
PN (Polynucleotide) · Self-Regeneration Induction
PN is an ingredient purified from the germ cells of salmon and trout.
Because its composition is similar to human DNA, it has high biocompatibility,
and when injected into the dermis, it is known to induce cellular self-regeneration and collagen synthesis.
Hyaluronic Acid (HA) · Moisture and Hydration
Hyaluronic acid is a substance naturally present in our skin,
and it is reported to have the property of attracting more than 1,000 times its own volume in moisture.
In Rejuran HB, HA plays three roles.
First, it fills the skin with hydration and a dewy glow,
second, it lowers the viscosity of the PN ingredient to alleviate injection irritation,
and third, it is known to extend the time PN stays in the dermis, multiplying the regenerative effect.
Lidocaine · Local Anesthetic
Lidocaine is a local anesthetic ingredient.
Because the formulation itself contains an anesthetic, it helps reduce pain at the moment of injection.
According to the manufacturer's clinical results, pain is reported to be reduced by approximately 53% compared to the original Rejuran Healer.
Effects and Advantages of Uijeongbu Rejuran HB
👉 Uijeongbu Rejuran HB is an option that approaches three effects—self-collagen regeneration, hydration/glow, and pain reduction—in a single treatment.
Self-Collagen Regeneration Induction
The PN ingredient activates collagen regeneration signals in the dermis,
approaching natural elasticity and fine line reduction created by your own tissues.
It is known for natural changes because it is a result created by your own body, rather than filling with foreign substances.
Hydration and Glow Effect
The HA ingredient provides immediate moisture and a subtle dewy glow to the skin.
You can usually see a moist surface and smooth radiance for several days after the procedure,
and it is often used as a care treatment to boost skin condition before important events.
Reduced Pain Burden
Thanks to the inclusion of lidocaine and the viscosity adjustment by HA, pain is significantly reduced,
making it comfortable even for those sensitive to pain.
It is frequently used as an option for those who hesitated due to the pain of the original Rejuran Healer.
Combination Options for the Rejuran Line
👉 Uijeongbu Rejuran HB can be used as a standalone treatment or in combination with other Rejuran lines or Juvelook.
Rejuran HB + Eye Rejuran Full-Face Combination
This is a combination where the entire face is treated with Rejuran HB, and the eye area is precisely managed with Eye Rejuran.
Eye Rejuran is a Rejuran specifically designed for the thin and sensitive eye area,
making it a suitable option when you want to treat both the entire face and the eye area.
Rejuvelook Combination · Rejuran + Juvelook
This combination adds the collagen booster effect of Juvelook to the regeneration and hydration effects of Rejuran HB.
Juvelook is a collagen booster that induces self-collagen production with PDLLA ingredients,
so you can also address pore improvement as the regeneration of Rejuran and the collagen stimulation of Juvelook overlap.
This combination includes the use of a High-Cooks injector for precise dermal injection.
Combination Selection Guide
Face regeneration + Eye precision care → Rejuran HB + Eye Rejuran Full-Face
Regeneration + Pores · Collagen → Rejuvelook (Rejuran + Juvelook)
Let's discuss which combination suits your skin concerns during the pre-procedure consultation.
Who is Uijeongbu Rejuran HB for?
Those who want the regenerative effects of Rejuran but were burdened by the pain
Those who want to address skin regeneration, fine line reduction, and hydration together
Those who feel their self-regeneration ability has decreased since their late 30s
Those who want dermal regeneration that is difficult to achieve with home care
Those who want to regularly manage their overall facial condition
Those who want to manage both the eye area and the face (Eye Rejuran combination option)
⚠️ Precautions Before and After Uijeongbu Rejuran HB
👉 Uijeongbu Rejuran HB is an option where result stability and recovery speed depend on pre-procedure condition management and post-procedure moisturizing and UV protection.
Uijeongbu Rejuran HB Side Effects and Things to Know in Advance
👉 Although Uijeongbu Rejuran HB is a treatment composed of highly biocompatible ingredients,
initial reactions may vary depending on individual skin conditions and ingredient responses.
Immediately after the procedure, redness, minor swelling, and temporary embossing marks may appear on the treated area.
Embossing is known as a natural sign that the ingredient has been accurately injected into the dermis,
and it usually clears up naturally within 1 to 3 days.
For sensitive skin, minor reactions may persist for a few days.
Although PN is a salmon-derived ingredient, it is a highly purified substance,
so it is reported that allergy-causing proteins have been removed.
However, if you have a severe seafood allergy, please be sure to inform us during the pre-procedure consultation.
Since it contains lidocaine, the procedure may be restricted if you have a history of lidocaine allergy.
The results of the procedure accumulate over several sessions,
so regular sessions of 3 or more at 2-3 week intervals are important for satisfaction.It is a treatment where stable improvement is confirmed through cumulative sessions rather than a dramatic change from a single session.If any of the following apply, the procedure may be restricted or require prior confirmation, so please inform us during the consultation.
If you are pregnant or breastfeeding
If you have a history of salmon or seafood allergies
If you have a history of lidocaine allergy
If you have active infections, wounds, or herpes in the treatment area
If you are regularly taking anticoagulants or antiplatelet agents, or have a bleeding tendency
If you have been diagnosed with autoimmune diseases or keloid tendencies
If you have a history of filler or thread procedures in the treatment area recently
❓ Frequently Asked Questions (FAQ)
Q. When can I see the results of Uijeongbu Rejuran HB?
You can feel the moist hydration from the hyaluronic acid immediately after the procedure,
and the regenerative results from the PN ingredient are usually seen gradually starting from 2-3 weeks.
It is known that regenerative results become stable when performed regularly 3 or more times at 2-3 week intervals.
Q. How is Uijeongbu Rejuran HB different from the original Rejuran Healer?
The basic ingredient, PN, is the same, but HB is an upgraded product with added hyaluronic acid and lidocaine.
According to the manufacturer's clinical trials, lidocaine reduces pain by about 53%,
and hyaluronic acid plays a role in providing a glow effect and extending the duration of PN.
Q. What should I do if embossing occurs after the Uijeongbu Rejuran HB procedure?
Embossing is known as a natural sign that the ingredient has settled accurately in the dermis.
It usually clears up naturally within 1 to 3 days,
and to help it clear faster, please refrain from massaging the treated area and focus on moisturizing.
Q. How many sessions of Uijeongbu Rejuran HB should I receive?
Generally, 3 or more regular sessions at 2-3 week intervals are recommended,
followed by maintenance care at 3-6 month intervals to sustain the results.
It is an option where results stabilize through cumulative sessions rather than a dramatic change from a single treatment.
Q. Can I receive Uijeongbu Rejuran HB and Eye Rejuran together?
Yes, it is possible.
At our Uijeongbu branch, we offer a full-face combination option where the entire face is treated with Rejuran HB and the eye area is precisely managed with Eye Rejuran,
so it is a suitable method when you want to manage both the face and the eye area.
Q. What are the effects of combining Juvelook with Uijeongbu Rejuran HB?
This is a combination that adds the collagen booster effect of Juvelook to the regeneration and hydration of Rejuran.
Juvelook's PDLLA ingredient induces self-collagen production, allowing you to address pores as well,
and it includes the use of a High-Cooks injector for precise dermal injection.
Q. How much is the pain reduced with Uijeongbu Rejuran HB?
According to the manufacturer's clinical results, pain is reported to be reduced by approximately 53% compared to the original Rejuran Healer.
Thanks to the inclusion of lidocaine and the viscosity adjustment by hyaluronic acid,
it is comfortable even for those sensitive to pain.
If you wanted the regenerative effects of Rejuran but hesitated due to the pain burden,
Uijeongbu Rejuran HB can be a suitable alternative.
It is an upgraded option that adds hyaluronic acid and lidocaine to the PN ingredient of the original Rejuran Healer,
reducing pain by more than half while maintaining regenerative effects.
At our Uijeongbu branch, we offer various Rejuran line options in addition to Rejuran HB.
From the Rejuran + Eye Rejuran full-face combination for managing the entire face and eye area,
to the Rejuran + Juvelook (Rejuvelook) combination for those who want both regeneration and a collagen booster,
you can choose the direction that suits your treatment area and goals.
We will personally check the direction that suits your skin condition and management goals during the consultation.
If you want to receive treatment comfortably with the same regenerative effects but lower pain burden,
please feel free to visit Cleor Clinic Uijeongbu Branch.
Even before deciding on the procedure, you can check your skin condition and a suitable session plan through a pre-procedure consultation.
※ This content is for general information purposes only, and results may vary by individual.
Please decide on accurate diagnosis and procedure through consultation with a specialist.
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