Uijeongbu palm Botox: If your palms are slippery due to damp sweat

July 1, 2026

Hello.

I am Director Jo Hyeok-chan of Cleor Clinic Uijeongbu Branch.

Have you ever felt hesitant to shake hands because your palms are sweaty regardless of the season or temperature,

or have you ever been concerned about leaving fingerprints on documents?

"I am cautious because people react noticeably even just from a handshake.

Sometimes I leave fingerprints when touching paper, and my smartphone touch screen doesn't work well."

Palmar sweating is not simply caused by heat.

Eccrine sweat glands are densely distributed in the palms,

and as the sympathetic nervous system controls these sweat glands,

it is structured to react significantly to stimuli such as tension, stress, and temperature changes.

Those with a tendency toward hyperhidrosis experience excessive palmar sweating even under the same conditions,

making daily contacts like handshakes, documents, touchscreens, and door handles a burden.

Uijeongbu Palmar Botox is a treatment that acts precisely on these palmar sweating signals.

Today, I will summarize the principles of how Uijeongbu Palmar Botox works,

and the specific precautions for palms that differ from underarm procedures.

What is Uijeongbu Palmar Botox

👉 Uijeongbu Palmar Botox is a primary palmar hyperhidrosis care treatment that precisely injects Botulinum Toxin Type A into the sympathetic nerve endings that control palmar sweat glands

to block acetylcholine secretion for a certain period.

The core of its action is blocking nerve terminal signals.

Sweat glands are activated when the sympathetic nervous system secretes a neurotransmitter called acetylcholine,

and Botulinum Toxin is an ingredient that blocks this acetylcholine secretion itself for a certain period.

The palms, along with the underarms, are the most common areas for primary focal hyperhidrosis,

and it is a treatment category that has official indications for hyperhidrosis from both the Ministry of Food and Drug Safety and the US FDA.

It is not a procedure that removes the sweat glands themselves, but rather manages the sweating signals,

so it is a cumulative care line where nerve function recovers and sweat is secreted again after a certain period.

Palmar Botox Mechanism

👉 Uijeongbu Palmar Botox is summarized by four action structures: blocking nerve terminal acetylcholine secretion, shallow multi-layer injection, immediate action, and nerve recovery after time.

Blocking nerve terminal acetylcholine secretion

When Botulinum Toxin Type A binds to the sympathetic nerve endings in the palm area,

  • the process of acetylcholine secretion is blocked for a certain period.

It is an action structure where sweating itself is reduced as signals do not reach the sweat glands.

Shallow multi-layer injection

Since sweat glands are located in the upper dermis,

  • it is a procedure method injected finely in shallow layers across the entire palm area.

The reason it is precisely divided into multiple points rather than injected into one spot

is to ensure an even effect while minimizing the possibility of diffusion into the intrinsic muscle layer of the palm.

Immediate action

A reduction in sweating begins to be felt about 3 to 7 days after the procedure,

  • and the greatest change is reported at about 2 weeks.

It is a line that does not require waiting for growth cycles like laser hair removal.

Nerve recovery after time

The blocked nerve endings recover their function as new nerve branches form over time.

  • Generally, sweating resumes between 4 to 9 months,

so it is a category where additional procedures are recommended according to the season or schedule.

Differences between palmar and underarm procedures

👉 While Palmar Botox has the same mechanism as underarm procedures, it is an area that requires special attention regarding pain management and the possibility of muscle weakness due to the characteristics of the treatment site.

Dense sensory nerves — Pain management required

The palm is one of the areas with the most densely packed sensory nerves in the body.

  • Since even the same micro-injection can feel more stimulating than in the underarms,

it is a line that utilizes pain management options such as topical anesthetic cream application, ice packs, and air anesthesia.

⚠️ Possibility of temporary muscle weakness

The palm is structured with small muscles (intrinsic muscles) located under the epidermis.

If Botulinum Toxin is injected too deeply or the dosage is excessive,

there have been cases of temporary hand muscle weakness or sensory abnormalities reported as it diffuses into the muscle layer.

Although most cases recover over time,

it is a side effect category that requires special attention for occupations that require precise hand use.

Pre-consultation is important for precision-work occupations

For those whose precise hand movements are essential to their professional activities, such as musicians, surgical medical staff, artists, and precision engineers,

  • it is recommended to decide whether to proceed and the timing of the procedure through sufficient consultation before the treatment.

Incidence of compensatory sweating

Compensatory sweating, where sweat increases in other areas, is a general side effect of hyperhidrosis Botox,

but it is known to have a relatively low incidence in palmar procedures.

  • Hyperhidrosis Botox effects and advantages

👉 The core advantages of Palmar Botox are summarized into three points: approaching the sweating signal itself, feeling daily life improvements, and low burden of non-surgical recovery.

First, it approaches the sweating signal itself.

Because it is a method that manages nerve transmission rather than the sweat glands themselves,

it is reported that the amount of palmar sweat secretion itself decreases.

Next, it is a line with significant daily life improvement.

It is known that burdens in daily contacts such as handshakes, document contact, smartphone touchscreen operation, and using door handles are resolved from 2 weeks after the procedure.

Finally, it is a non-surgical procedure, so the recovery burden is low.

As it is a line performed with micro-injections without incisions,

it is reported that the procedure time is short and daily activities are possible from the day of the procedure.

Lineup

👉 At the Uijeongbu branch, we operate hyperhidrosis Botox for underarm, hand, and foot areas with 2 types of toxins (domestic and domestic premium) × 100-unit and 200-unit options.

100 units are recommended when the amount of sweating is relatively mild or you want to check the feeling of the procedure first,

and 200 units are recommended when the amount of sweating is high or you want to have extensive care for both hands.

We will examine the combination that suits your degree of palmar hyperhidrosis and toxin preference together during the pre-consultation.

Recommended for these people

Those who have excessive palmar sweating regardless of the season

Those who feel burdened by contact with handshakes, documents, touchscreens, and door handles

Those who become cautious about their hand posture in meetings, presentations, or dates

Those who have both underarm/foot hyperhidrosis and palmar hyperhidrosis

  • Those who want to manage it every season through repeated cumulative care

  • Side effects and things to know in advance

  • 👉 Uijeongbu Palmar Botox is a line with proven safety, but it is good to understand the possibility of muscle weakness in advance due to the nature of the hand procedure.

  • Light redness, micro-bruising, and swelling may accompany the treated area immediately after the procedure.

  • Most cases are reported to subside naturally within a few days.

As mentioned earlier, the palm has intrinsic muscles located under the epidermis,

so there have been cases of temporary muscle weakness or sensory abnormalities reported if Botulinum Toxin diffuses into the muscle layer.

Although most cases recover naturally over time,

it is a line where sufficient consultation is recommended before the procedure for those whose precise hand use is essential to their professional activities.

As the possibility of resistance is reported in some cases with repeated procedures,

it is recommended to organize the procedure cycle and toxin line selection together during the pre-consultation if you are undergoing long-term repeated care.

Please inform us in advance as the procedure may be restricted in the following cases:

If you are pregnant or breastfeeding

If you have a history of allergies or hypersensitivity reactions to Botulinum Toxin ingredients

If you have been diagnosed with neuromuscular diseases such as myasthenia gravis

If you are taking medications that affect toxin action, such as antibiotics (aminoglycoside class)

If there is an active infection at the treatment site

  • ⚠️ Precautions before and after the procedure

  • 👉 Palmar Botox management by time before and after the procedure affects the stability of the effect and the possibility of side effects.

  • ❓ Frequently Asked Questions (FAQ)

  • Q. When does the Palmar Botox effect appear?

  • A reduction in palmar sweating begins to be felt about 3 to 7 days after the procedure,

and the greatest change is reported at about 2 weeks.

It is an area where there are differences in the onset time depending on individual constitution.

Q. How long does the maintenance period last?

It generally lasts for about 4 to 9 months.

There are individual differences depending on individual metabolic rate, amount of sweating, and procedure dosage,

and it is a category where cases have been reported where the maintenance period gradually increases with repeated procedures.

Q. Is it true that hand muscle strength can weaken?

The palm is structured with intrinsic muscles located under the epidermis,

so there have been cases of temporary muscle weakness or sensory abnormalities reported if Botulinum Toxin diffuses into the muscle layer.

While we minimize the possibility of diffusion by injecting it into shallow layers with micro-needles,

sufficient consultation is recommended before the procedure for those whose precise hand use is essential to their professional activities.

Q. How should I choose between 100 units and 200 units?

It is an area determined by the amount of sweating and the palm area.

100 units are recommended when the amount of sweating is relatively mild or you want to check the feeling of the procedure first,

and 200 units are recommended when the amount of sweating is high or you want to have extensive care for both hands.

Q. How much does it hurt?

Since the palm is an area where sensory nerves are densely packed, it can feel more stimulating than the underarms.

It is a line that utilizes pain management options such as topical anesthetic cream application, ice packs, and air anesthesia.

Q. Can I receive it along with underarms/soles?

In cases where hyperhidrosis tendencies are accompanied in multiple areas,

it is an area where it is sometimes performed together by area.

At the Uijeongbu branch, hyperhidrosis Botox is operated for underarm, hand, and foot areas,

so we will examine your sweating condition and area combination together during the pre-consultation.

Q. Doesn't sweat increase in other areas?

Although there are rare cases of compensatory sweating reported,

it is known to have a relatively low incidence in palmar procedures.

It is a category where consultation is recommended if it is severely accompanied.

Palmar hyperhidrosis is not just a simple constitution, but a multi-factorial change where autonomic nervous system regulation and sweat gland activity work together.

It is an area that affects daily contacts such as handshakes, documents, touchscreens, and door handles,

which is why a line that approaches the sweating signal itself has become established.

Uijeongbu Palmar Botox is a primary hyperhidrosis care treatment that precisely injects Botulinum Toxin Type A into the sympathetic nerve endings that control palmar sweat glands to block acetylcholine secretion for a certain period.

However, since the palm is structured with intrinsic muscles located under the epidermis, it is good to understand together that it is a line where sufficient consultation is especially recommended before the procedure for those for whom precise hand use is essential.

At the Uijeongbu branch, we operate hyperhidrosis Botox for underarm, hand, and foot areas.

It is performed with 2 types of toxins (domestic and domestic premium) × 100-unit and 200-unit options, so it is a structure that can be selected according to your hyperhidrosis area and amount of sweating.

We will check the toxin and unit configuration that suits your condition directly during the consultation.

If you are concerned about hand sweat during handshakes, document work, and touchscreen operation, please feel free to visit Cleor Clinic Uijeongbu Branch.

Even before deciding on the procedure, we will provide detailed guidance on your hand condition and suitable care direction through a pre-consultation.

※ This content is for general information purposes, and results may vary by individual.

Please decide on accurate diagnosis and whether to proceed with the procedure through consultation with a specialist.

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