If you are curious about the principle of delivering Ionzyme active ingredients deep into the dermis layer in Uijeongbu

September 1, 2026

Hello.

I am Dr. Hyuk-chan Jo, Director of Cleor Clinic Uijeongbu Branch.

Have you ever felt frustrated because your skin doesn't seem to change much,

even though you apply vitamin ampoules or whitening products every day?

"I apply all the products that are supposed to be good, but there's no real change.

I wonder if the ingredients are actually penetrating my skin properly,

and if there is a professional treatment that can fundamentally deliver them into the skin."

This is actually a concern many people have.

Generally, the active ingredients in cosmetics are blocked by the skin's surface barrier,

so the rate at which they reach the dermis layer below the epidermis is very low.

Because of this fundamental limitation, even with the best ingredients,

it is often difficult to achieve consistent results through home care.

The professional treatment technology that solves this penetration limitation is Uijeongbu Iontozyme.

Today, I will explain the principles of how Iontozyme delivers ingredients to the dermis,

what programs it is used in, and how it differs from home care.

What is Uijeongbu Iontozyme?

👉 Uijeongbu Iontozyme is a premium penetration treatment technology that uses both Iontophoresis and Sonophoresis simultaneously

to deliver active ingredients deep into the dermis layer.

Iontozyme is often used as a core technology in premium aesthetic programs

rather than as a standalone treatment.

Treatments including Iontozyme maximize the penetration rate of active ingredients,

creating results that are difficult to achieve with home care.

At the Uijeongbu branch, we offer 'Lala-Zyme', a premium aesthetic program that includes Iontozyme,

which you can proceed with according to your regular care plan.

The Principle of Iontozyme - Simultaneous Use of Two Technologies

👉 Uijeongbu Iontozyme maximizes penetration by simultaneously using two principles: pushing ingredients in with Iontophoresis,

and opening skin pathways with ultrasound.

  • Iontophoresis

This method applies a micro-current to ionized ingredients

to push them into the skin.

It is a principle that allows even water-soluble vitamins, which do not easily pass through the epidermis,

to be delivered to the dermis through the power of electricity.

  • Sonophoresis (Ultrasound)

When low-frequency ultrasonic vibrations are delivered to the skin,

micro-pathways are created in the stratum corneum and lipid layers.

This creates conditions where ingredients can penetrate much more easily through these pathways.

  • Synergy of the Two Principles

As Iontophoresis and ultrasound work simultaneously,

the ingredient penetration rate increases significantly compared to home care.

By combining the two principles of pushing with electrical force

and opening pathways with ultrasound,

active ingredients such as Vitamin C, A (Retinol), E, and AHA are delivered deep into the dermis.

The Decisive Difference from Home Care

👉 While the active ingredients in regular cosmetics are blocked by the epidermal barrier and have a very low dermal delivery rate,

Uijeongbu Iontozyme is an approach that fundamentally solves this limitation with two penetration technologies.

  • The Wall of the Epidermal Barrier

Our skin surface has a barrier that prevents external irritation and moisture loss.

While this barrier plays a role in protecting the skin,

it also prevents active ingredients from entering the skin.

In particular, water-soluble vitamin ingredients often cannot pass through the barrier well,

so they often remain on the surface of the epidermis and disappear without being absorbed.

Even the best ingredients are useless if they are not absorbed.

No matter how diligently you apply ampoules and creams containing good ingredients,

if they do not reach inside the skin, the results will not be significant.

This penetration limitation is the fundamental wall of home care.

  • Iontozyme's Approach - Passing Through the Epidermal Barrier

Iontozyme solves the limitations of this barrier with two technologies.

By combining Iontophoresis and ultrasound,

it delivers active ingredients through the barrier to the deep dermis layer,

making it a treatment with a completely different result direction than home care.

Premium Aesthetic 'Lala-Zyme' Using Iontozyme

👉 The program that maximizes the strengths of Uijeongbu Iontozyme is the premium aesthetic 'Lala-Zyme',

and the 5-step treatment is designed according to the order and combination to stably approach ingredient penetration results.

Lala-Zyme 5-Step Composition

Premium aesthetic Lala-Zyme is a 5-step integrated treatment centered on Iontozyme.

  • Step 1 · Lala Peel

This is a step to prepare the pathway for Iontozyme ingredient penetration by clearing dead skin cells with a mild LHA peeling.

Step 2 · Moisture Ultrasound

  • This delivers moisture ingredients into the skin through ultrasonic vibrations

and creates favorable conditions for the ingredients in the next steps to settle.

Step 3 · Sothys Ampoule

  • This is a step to approach skin condition recovery by applying Sothys ampoules specialized for regeneration and soothing.

Step 4 · Iontozyme

This is the core step that delivers active ingredients deep into the dermis using Iontophoresis and ultrasound.

  • Because Iontozyme is performed on skin prepared in the previous steps,

the ingredient penetration efficiency is maximized.

Step 5 · Modeling Pack

We finish with a modeling pack to soothe the skin irritated during the procedure

  • and ensure the ingredients settle stably.

Choosing a Program According to Treatment Purpose

👉 In addition to Lala-Zyme, which includes Iontozyme, the Uijeongbu branch also operates various aesthetic programs

that you can choose according to your treatment purpose and comfort level.

Premium Aesthetic Lala-Zyme · 5 Steps Including Iontozyme

This is a premium treatment program that includes Iontozyme's dermal ingredient penetration technology.

  • It combines 5 steps: Lala Peel, Moisture Ultrasound, Sothys Ampoule, Iontozyme, and Modeling Pack,

to comprehensively approach ingredient penetration and regeneration care.

Smooth Egg Lala Peel · Specialized in Exfoliation

This is a program focused on exfoliation and hydration.

  • It consists of 3 steps: Lala Peel, Moisture Ultrasound, and Modeling Pack,

and is suitable when you want smooth skin texture and tone improvement.

Selection Guide According to Purpose

If you need ingredient penetration and comprehensive care → Lala-Zyme

If exfoliation and texture improvement are your priority → Smooth Egg Lala Peel

If intensive hydration is needed → 48-Hour Moisture Care

We will review your skin condition, treatment purpose, and session plan together during the pre-treatment consultation.

Main Effects of Iontozyme

👉 Uijeongbu Iontozyme delivers ionized active ingredients to the dermis,

approaching comprehensive skin condition improvement such as whitening, regeneration, tone improvement, and fine line reduction.

Whitening, Melasma, and Blemish Improvement (Vitamin C penetration)

Collagen Production Promotion & Fine Line Reduction (Vitamin A/Retinol penetration)

  • Anti-aging & Photo-aging Delay (Vitamin E penetration)

  • Skin Regeneration and Tone Improvement

  • Moisture and Elasticity Recovery

  • Soothing and Condition Management after Peeling/Laser Procedures

  • Who is Iontozyme Suitable For?

  • Those who feel that cosmetics are not absorbed well

Those who need whitening, melasma, and blemish care

  • Those who want comprehensive skin texture, tone, and moisture care

  • Those who want professional care because home care has limitations

  • Those who want low-irritation premium care

  • Those who want to create a regular skin care routine

  • Uijeongbu Iontozyme Side Effects and Things to Know in Advance

  • 👉 Although Uijeongbu Iontozyme is a low-irritation premium treatment technology,

initial reactions may vary depending on individual skin condition and sensitivity.

Light redness may persist in the treated area for a few days immediately after the procedure.

Generally, it clears up naturally within a day.

In the case of sensitive skin, minor reactions may continue for a few days.

Since the Iontozyme step uses micro-current and ultrasound simultaneously,

rarely, there may be a slight tingling sensation during the procedure, but it is at a low level of discomfort.

Although the LHA ingredient in the Lala Peel step included in the premium aesthetic Lala-Zyme is mild,

the skin may show sensitive reactions during the first treatment,

so intensity adjustment tailored to your skin condition is performed during the pre-treatment consultation.

Due to the nature of regular care, rather than a dramatic change with a single treatment,

it is a direction where the condition is stably maintained through consistent progress.

If any of the following apply to you, treatment may be restricted or

prior confirmation may be required, so please inform us during the consultation.

If you are pregnant or breastfeeding

If you have a cardiac pacemaker or metal implants

  • If you have active infections, wounds, or herpes in the treatment area

  • If you have a history of recent strong peeling or laser procedures

  • If you have severe acne or inflammatory skin conditions

  • If you have a history of allergies to specific ingredients

  • If you are taking isotretinoin (sebum inhibitor)

  • ⚠️ Precautions Before and After Iontozyme Treatment

  • 👉 Iontozyme is a treatment program where result sustainability varies depending on post-treatment moisturizing and UV protection.

❓ Frequently Asked Questions (FAQ)

Q. When can I see the results of Iontozyme?

You can feel the change in skin tone and texture immediately after the procedure.

When performed regularly at 2-4 week intervals, the condition tends to settle stably.

Accumulating sessions is more important for satisfaction than a single treatment.

Q. How is it different from home care?

While home care focuses on epidermal surface care,

Iontozyme is a method that delivers active ingredients to the dermis

using Iontophoresis and ultrasound technology.

It is an ingredient penetration method that cannot be accessed through home care,

so the strengths of professional care are distinct.

Q. Can I receive Iontozyme alone?

At the Uijeongbu branch, we do not perform Iontozyme alone.

It is included as a core step of the premium aesthetic Lala-Zyme program,

designed so that results settle stably when combined with the preceding and following steps.

Q. Is there pain or irritation during the procedure?

Since it uses micro-current and ultrasound simultaneously, there is no strong pain.

Rarely, there may be a slight tingling or stinging sensation during the procedure,

but you can receive it comfortably as it is at a low level of discomfort.

Q. Can it be combined with other procedures?

Yes, it is possible.

Lala-Zyme treatment including Iontozyme is frequently used before and after laser or lifting procedures

for skin soothing and condition management.

The order and interval of the two procedures are decided during the pre-treatment consultation.

Q. How many sessions should I receive?

You can feel an immediate change with a single treatment.

When performed regularly 5 to 10 times, results accumulate stably

and skin condition improves fundamentally, so creating a regular care routine is suitable for satisfaction.

Q. Can sensitive skin receive it?

Iontozyme is a low-irritation premium treatment technology, so it is less burdensome even for sensitive skin.

Intensity adjustment tailored to your skin condition is performed during the pre-treatment consultation,

and it is suitable to start with lower intensity for the first treatment.

Even if cosmetics contain the best ingredients, if they are blocked by the epidermal barrier,

they often disappear from the surface without reaching inside the skin.

The professional treatment technology that fundamentally solves this penetration limitation is Uijeongbu Iontozyme.

Iontozyme is a premium penetration technology that delivers active ingredients deep into the dermis layer

by using both Iontophoresis and ultrasound technologies simultaneously.

At the Uijeongbu branch, we operate the premium aesthetic 'Lala-Zyme'

which maximizes the strengths of Iontozyme.

The 5 steps—Lala Peel, Moisture Ultrasound, Sothys Ampoule, Iontozyme, and Modeling Pack—are designed according to order and combination,

approaching ingredient penetration and regeneration care comprehensively.

In addition to Lala-Zyme, we also operate other aesthetic programs suitable for your management goals,

such as the Smooth Egg Lala Peel specialized for exfoliation,

and 48-Hour Moisture Care suitable when intensive hydration is needed.

We will personally check the direction suitable for your skin condition and management goals

during the consultation.

If you want dermal layer care that cannot be reached through home care,

please feel free to visit Cleor Clinic Uijeongbu Branch.

Even before deciding on a procedure, you can review a program plan

suitable for your skin condition through a pre-treatment consultation.

※ This content is for general information purposes only, and results may vary by individual.

Please decide on accurate diagnosis and whether to proceed with the procedure through a specialist consultation.

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